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The relationship between folding and activity in UreG, an intrinsically disordered enzyme
A growing body of literature on intrinsically disordered proteins (IDPs) led scientists to rethink the structure-function paradigm of protein folding. Enzymes are often considered an exception to the rule of intrinsic disorder (ID), believed to require a unique structure for catalysis. However, rece...
Autores principales: | Palombo, Marta, Bonucci, Alessio, Etienne, Emilien, Ciurli, Stefano, Uversky, Vladimir N., Guigliarelli, Bruno, Belle, Valérie, Mileo, Elisabetta, Zambelli, Barbara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519622/ https://www.ncbi.nlm.nih.gov/pubmed/28729736 http://dx.doi.org/10.1038/s41598-017-06330-9 |
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