A population-specific reference panel empowers genetic studies of Anabaptist populations

Genotype imputation is a powerful strategy for achieving the large sample sizes required for identification of variants underlying complex phenotypes, but imputation of rare variants remains problematic. Genetically isolated populations offer one solution, however population-specific reference panel...

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Detalles Bibliográficos
Autores principales: Hou, Liping, Kember, Rachel L., Roach, Jared C., O’Connell, Jeffrey R., Craig, David W., Bucan, Maja, Scott, William K., Pericak-Vance, Margaret, Haines, Jonathan L., Crawford, Michael H., Shuldiner, Alan R., McMahon, Francis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519631/
https://www.ncbi.nlm.nih.gov/pubmed/28729679
http://dx.doi.org/10.1038/s41598-017-05445-3

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