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Effects of 4(1H)-quinolinone derivative, a novel non-nucleotide allosteric purinergic P2Y(2) agonist, on cardiomyocytes in neonatal rats
Purinergic P2Y(2) receptors, G-protein coupled receptors that primarily couple with Gα(q/11)-proteins, are activated equipotently by adenosine-5′-triphosphate (ATP) and uridine-5′-triphosphate. Evidence suggests that P2Y(2) agonists make potential drug candidates for the treatment of cardiovascular...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519634/ https://www.ncbi.nlm.nih.gov/pubmed/28729619 http://dx.doi.org/10.1038/s41598-017-06481-9 |