Engineering Tumour Cell-Binding Synthetic Polymers with Sensing Dense Transporters Associated with Aberrant Glutamine Metabolism

Increased glutamine uptake toward the elevated glutaminolysis is one of the hallmarks of tumour cells. This aberrant glutamine metabolism has recently attracted considerable attention as a diagnostic and therapeutic target. Herein, we developed glutamine-functionalized polymer to achieve a selective...

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Detalles Bibliográficos
Autores principales: Yamada, Naoki, Honda, Yuto, Takemoto, Hiroyasu, Nomoto, Takahiro, Matsui, Makoto, Tomoda, Keishiro, Konno, Masamitsu, Ishii, Hideshi, Mori, Masaki, Nishiyama, Nobuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519697/
https://www.ncbi.nlm.nih.gov/pubmed/28729677
http://dx.doi.org/10.1038/s41598-017-06438-y

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