Weakened IL-15 Production and Impaired mTOR Activation Alter Dendritic Epidermal T Cell Homeostasis in Diabetic Mice

Diabetes is associated with impaired wound healing, which may be caused primarily by a deficiency in dendritic epidermal T cells (DETCs). In the epidermis, IL-15, IGF-1, and mTOR are known to regulate the maintenance of DETCs; however, it is unclear how these molecules may intersect to regulate DETC...

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Detalles Bibliográficos
Autores principales: Liu, Zhongyang, Liang, Guangping, Gui, Li, Li, Yashu, Liu, Meixi, bai, Yang, Zhang, Xiaorong, Hu, Xiaohong, Chen, Jian, Huang, Chibing, Liu, Xusheng, Luo, Gaoxing, Wu, Jun, He, Weifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519720/
https://www.ncbi.nlm.nih.gov/pubmed/28729536
http://dx.doi.org/10.1038/s41598-017-05950-5

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