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Subthalamic nucleus deep brain stimulation is neuroprotective in the A53T α‐synuclein Parkinson's disease rat model

OBJECTIVE: Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a highly effective symptomatic therapy for motor deficits in Parkinson's disease (PD). An additional, disease‐modifying effect has been suspected from studies in toxin‐based PD animal models, but these models do not ref...

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Detalles Bibliográficos
Autores principales: Musacchio, Thomas, Rebenstorff, Maike, Fluri, Felix, Brotchie, Jonathan M., Volkmann, Jens, Koprich, James B., Ip, Chi Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519923/
https://www.ncbi.nlm.nih.gov/pubmed/28470693
http://dx.doi.org/10.1002/ana.24947