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Spontaneous CD4(+) and CD8(+) T‐cell responses directed against cancer testis antigens are present in the peripheral blood of testicular cancer patients
Cancer/testis antigen (CTAg) expression is restricted to spermatogenic cells in an immune‐privileged site within the testis. However, these proteins are expressed aberrantly by malignant cells and T‐cell responses against CTAgs develop in many cancer patients. We investigated the prevalence, magnitu...
Autores principales: | Pearce, Hayden, Hutton, Paul, Chaudhri, Shalini, Porfiri, Emilio, Patel, Prashant, Viney, Richard, Moss, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519936/ https://www.ncbi.nlm.nih.gov/pubmed/28555838 http://dx.doi.org/10.1002/eji.201646898 |
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