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Route of Administration Affects Corticosteroid Sensitivity of a Combined Ovalbumin and Lipopolysaccharide Model of Asthma Exacerbation in Guinea Pigs
Lipopolysaccharide (LPS) contributes to asthma exacerbations and development of inhaled corticosteroid insensitivity. Complete resistance to systemic corticosteroids is rare, and most patients lie on a continuum of steroid responsiveness. This study aimed to examine the sensitivity of combined ovalb...
Autores principales: | Lowe, Alexander P. P., Thomas, Rhian S., Nials, Anthony T., Kidd, Emma J., Broadley, Kenneth J., Ford, William R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Pharmacology and Experimental Therapeutics
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520105/ https://www.ncbi.nlm.nih.gov/pubmed/28576975 http://dx.doi.org/10.1124/jpet.117.241927 |
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