miR-199a impairs autophagy and induces cardiac hypertrophy through mTOR activation

Basal autophagy is tightly regulated by transcriptional and epigenetic factors to maintain cellular homeostasis. Dysregulation of cardiac autophagy is associated with heart diseases, including cardiac hypertrophy, but the mechanism governing cardiac autophagy is rarely identified. To analyze the in...

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Detalles Bibliográficos
Autores principales: Li, Z, Song, Y, Liu, L, Hou, N, An, X, Zhan, D, Li, Y, Zhou, L, Li, P, Yu, L, Xia, J, Zhang, Y, Wang, J, Yang, X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520159/
https://www.ncbi.nlm.nih.gov/pubmed/26160071
http://dx.doi.org/10.1038/cdd.2015.95

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