Signalome-wide RNAi screen identifies GBA1 as a positive mediator of autophagic cell death

Activating alternative cell death pathways, including autophagic cell death, is a promising direction to overcome the apoptosis resistance observed in various cancers. Yet, whether autophagy acts as a death mechanism by over consumption of intracellular components is still controversial and remains...

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Detalles Bibliográficos
Autores principales: Dasari, Santosh K, Bialik, Shani, Levin-Zaidman, Smadar, Levin-Salomon, Vered, Merrill, Alfred H, Futerman, Anthony H, Kimchi, Adi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520177/
https://www.ncbi.nlm.nih.gov/pubmed/28574511
http://dx.doi.org/10.1038/cdd.2017.80

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