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Conjugated polymer nanomaterials for theranostics

Conjugated polymer nanomaterials (CPNs), as optically and electronically active materials, hold promise for biomedical imaging and drug delivery applications. This review highlights the recent advances in the utilization of CPNs in theranostics. Specifically, CPN-based in vivo imaging techniques, in...

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Autores principales: Qian, Cheng-gen, Chen, Yu-lei, Feng, Pei-jian, Xiao, Xuan-zhong, Dong, Mei, Yu, Ji-cheng, Hu, Quan-yin, Shen, Qun-dong, Gu, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520193/
https://www.ncbi.nlm.nih.gov/pubmed/28552910
http://dx.doi.org/10.1038/aps.2017.42
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author Qian, Cheng-gen
Chen, Yu-lei
Feng, Pei-jian
Xiao, Xuan-zhong
Dong, Mei
Yu, Ji-cheng
Hu, Quan-yin
Shen, Qun-dong
Gu, Zhen
author_facet Qian, Cheng-gen
Chen, Yu-lei
Feng, Pei-jian
Xiao, Xuan-zhong
Dong, Mei
Yu, Ji-cheng
Hu, Quan-yin
Shen, Qun-dong
Gu, Zhen
author_sort Qian, Cheng-gen
collection PubMed
description Conjugated polymer nanomaterials (CPNs), as optically and electronically active materials, hold promise for biomedical imaging and drug delivery applications. This review highlights the recent advances in the utilization of CPNs in theranostics. Specifically, CPN-based in vivo imaging techniques, including near-infrared (NIR) imaging, two-photon (TP) imaging, photoacoustic (PA) imaging, and multimodal (MM) imaging, are introduced. Then, CPN-based photodynamic therapy (PDT) and photothermal therapy (PTT) are surveyed. A variety of stimuli-responsive CPN systems for drug delivery are also summarized, and the promising trends and translational challenges are discussed.
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spelling pubmed-55201932017-07-26 Conjugated polymer nanomaterials for theranostics Qian, Cheng-gen Chen, Yu-lei Feng, Pei-jian Xiao, Xuan-zhong Dong, Mei Yu, Ji-cheng Hu, Quan-yin Shen, Qun-dong Gu, Zhen Acta Pharmacol Sin Review Conjugated polymer nanomaterials (CPNs), as optically and electronically active materials, hold promise for biomedical imaging and drug delivery applications. This review highlights the recent advances in the utilization of CPNs in theranostics. Specifically, CPN-based in vivo imaging techniques, including near-infrared (NIR) imaging, two-photon (TP) imaging, photoacoustic (PA) imaging, and multimodal (MM) imaging, are introduced. Then, CPN-based photodynamic therapy (PDT) and photothermal therapy (PTT) are surveyed. A variety of stimuli-responsive CPN systems for drug delivery are also summarized, and the promising trends and translational challenges are discussed. Nature Publishing Group 2017-06 2017-05-29 /pmc/articles/PMC5520193/ /pubmed/28552910 http://dx.doi.org/10.1038/aps.2017.42 Text en Copyright © 2017 CPS and SIMM http://creativecommons.org/licenses/by-nc-nd/3.0/ This work is licensed under the Creative Commons Attribution-NonCommercial-No Derivative Works 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/
spellingShingle Review
Qian, Cheng-gen
Chen, Yu-lei
Feng, Pei-jian
Xiao, Xuan-zhong
Dong, Mei
Yu, Ji-cheng
Hu, Quan-yin
Shen, Qun-dong
Gu, Zhen
Conjugated polymer nanomaterials for theranostics
title Conjugated polymer nanomaterials for theranostics
title_full Conjugated polymer nanomaterials for theranostics
title_fullStr Conjugated polymer nanomaterials for theranostics
title_full_unstemmed Conjugated polymer nanomaterials for theranostics
title_short Conjugated polymer nanomaterials for theranostics
title_sort conjugated polymer nanomaterials for theranostics
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520193/
https://www.ncbi.nlm.nih.gov/pubmed/28552910
http://dx.doi.org/10.1038/aps.2017.42
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