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Conjugated polymer nanomaterials for theranostics
Conjugated polymer nanomaterials (CPNs), as optically and electronically active materials, hold promise for biomedical imaging and drug delivery applications. This review highlights the recent advances in the utilization of CPNs in theranostics. Specifically, CPN-based in vivo imaging techniques, in...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520193/ https://www.ncbi.nlm.nih.gov/pubmed/28552910 http://dx.doi.org/10.1038/aps.2017.42 |
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author | Qian, Cheng-gen Chen, Yu-lei Feng, Pei-jian Xiao, Xuan-zhong Dong, Mei Yu, Ji-cheng Hu, Quan-yin Shen, Qun-dong Gu, Zhen |
author_facet | Qian, Cheng-gen Chen, Yu-lei Feng, Pei-jian Xiao, Xuan-zhong Dong, Mei Yu, Ji-cheng Hu, Quan-yin Shen, Qun-dong Gu, Zhen |
author_sort | Qian, Cheng-gen |
collection | PubMed |
description | Conjugated polymer nanomaterials (CPNs), as optically and electronically active materials, hold promise for biomedical imaging and drug delivery applications. This review highlights the recent advances in the utilization of CPNs in theranostics. Specifically, CPN-based in vivo imaging techniques, including near-infrared (NIR) imaging, two-photon (TP) imaging, photoacoustic (PA) imaging, and multimodal (MM) imaging, are introduced. Then, CPN-based photodynamic therapy (PDT) and photothermal therapy (PTT) are surveyed. A variety of stimuli-responsive CPN systems for drug delivery are also summarized, and the promising trends and translational challenges are discussed. |
format | Online Article Text |
id | pubmed-5520193 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-55201932017-07-26 Conjugated polymer nanomaterials for theranostics Qian, Cheng-gen Chen, Yu-lei Feng, Pei-jian Xiao, Xuan-zhong Dong, Mei Yu, Ji-cheng Hu, Quan-yin Shen, Qun-dong Gu, Zhen Acta Pharmacol Sin Review Conjugated polymer nanomaterials (CPNs), as optically and electronically active materials, hold promise for biomedical imaging and drug delivery applications. This review highlights the recent advances in the utilization of CPNs in theranostics. Specifically, CPN-based in vivo imaging techniques, including near-infrared (NIR) imaging, two-photon (TP) imaging, photoacoustic (PA) imaging, and multimodal (MM) imaging, are introduced. Then, CPN-based photodynamic therapy (PDT) and photothermal therapy (PTT) are surveyed. A variety of stimuli-responsive CPN systems for drug delivery are also summarized, and the promising trends and translational challenges are discussed. Nature Publishing Group 2017-06 2017-05-29 /pmc/articles/PMC5520193/ /pubmed/28552910 http://dx.doi.org/10.1038/aps.2017.42 Text en Copyright © 2017 CPS and SIMM http://creativecommons.org/licenses/by-nc-nd/3.0/ This work is licensed under the Creative Commons Attribution-NonCommercial-No Derivative Works 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/ |
spellingShingle | Review Qian, Cheng-gen Chen, Yu-lei Feng, Pei-jian Xiao, Xuan-zhong Dong, Mei Yu, Ji-cheng Hu, Quan-yin Shen, Qun-dong Gu, Zhen Conjugated polymer nanomaterials for theranostics |
title | Conjugated polymer nanomaterials for theranostics |
title_full | Conjugated polymer nanomaterials for theranostics |
title_fullStr | Conjugated polymer nanomaterials for theranostics |
title_full_unstemmed | Conjugated polymer nanomaterials for theranostics |
title_short | Conjugated polymer nanomaterials for theranostics |
title_sort | conjugated polymer nanomaterials for theranostics |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520193/ https://www.ncbi.nlm.nih.gov/pubmed/28552910 http://dx.doi.org/10.1038/aps.2017.42 |
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