Programmable co-delivery of the immune checkpoint inhibitor NLG919 and chemotherapeutic doxorubicin via a redox-responsive immunostimulatory polymeric prodrug carrier

To achieve synergistic therapeutic efficacy and prevent cancer relapse, chemotherapy and immunotherapy have been combined as a new modality for tumor treatment. In this work, we designed a redox-responsive immunostimulatory polymeric prodrug carrier, PSSN10, for programmable co-delivery of an immune...

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Detalles Bibliográficos
Autores principales: Sun, Jing-jing, Chen, Yi-chao, Huang, Yi-xian, Zhao, Wen-chen, Liu, Yan-hua, Venkataramanan, Raman, Lu, Bin-feng, Li, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520195/
https://www.ncbi.nlm.nih.gov/pubmed/28504251
http://dx.doi.org/10.1038/aps.2017.44

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