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Second-line pazopanib in patients with relapsed and refractory small-cell lung cancer: a multicentre phase II study of the Hellenic Oncology Research Group
BACKGROUND: Pazopanib is a tyrosine kinase inhibitor with antiangiogenic activity. Vascular endothelial growth factor expression is increased in SCLC and is correlated with poor prognosis. The efficacy and tolerance of second-line pazopanib in SCLC was evaluated. PATIENTS AND METHODS: Patients with...
Autores principales: | Koinis, F, Agelaki, S, Karavassilis, V, Kentepozidis, N, Samantas, E, Peroukidis, S, Katsaounis, P, Hartabilas, E, Varthalitis, I I, Messaritakis, I, Fountzilas, G, Georgoulias, V, Kotsakis, A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520202/ https://www.ncbi.nlm.nih.gov/pubmed/28510571 http://dx.doi.org/10.1038/bjc.2017.137 |
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