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Oncolytic alphavirus SFV-VA7 efficiently eradicates subcutaneous and orthotopic human prostate tumours in mice
BACKGROUND: Despite recent therapeutic and diagnostic advances, prostate cancer remains the second leading cause of cancer-related deaths among men in the Western world. Oncolytic viruses that replicate selectively in tumour cells represent a novel treatment candidate for these malignancies. METHODS...
Autores principales: | Martikainen, Miika, Ruotsalainen, Janne, Tuomela, Johanna, Härkönen, Pirkko, Essand, Magnus, Heikkilä, Jari, Hinkkanen, Ari |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520213/ https://www.ncbi.nlm.nih.gov/pubmed/28557974 http://dx.doi.org/10.1038/bjc.2017.151 |
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