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Genetic variants affecting cross-sectional lung function in adults show little or no effect on longitudinal lung function decline

BACKGROUND: Genome-wide association studies have identified numerous genetic regions that influence cross-sectional lung function. Longitudinal decline in lung function also includes a heritable component but the genetic determinants have yet to be defined. OBJECTIVES: We aimed to determine whether...

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Detalles Bibliográficos
Autores principales:	John, Catherine, Soler Artigas, María, Hui, Jennie, Nielsen, Sune Fallgaard, Rafaels, Nicholas, Paré, Peter D, Hansel, Nadia N, Shrine, Nick, Kilty, Iain, Malarstig, Anders, Jelinsky, Scott A, Vedel-Krogh, Signe, Barnes, Kathleen, Hall, Ian P, Beilby, John, Musk, Arthur W, Nordestgaard, Børge G, James, Alan, Wain, Louise V, Tobin, Martin D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2017
Materias:	Chronic Obstructive Pulmonary Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520280/ https://www.ncbi.nlm.nih.gov/pubmed/28174340 http://dx.doi.org/10.1136/thoraxjnl-2016-208448

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