Understanding the genetics behind complex human disease with large-scale iPSC collections

Three recent studies analyzing large-scale collections of human induced pluripotent stem cell lines provide valuable insight into how genetic regulatory variation affects cellular and molecular traits.

Detalles Bibliográficos
Autores principales: Yamasaki, Amanda E., Panopoulos, Athanasia D., Belmonte, Juan Carlos Izpisua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Highlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520285/
https://www.ncbi.nlm.nih.gov/pubmed/28728561
http://dx.doi.org/10.1186/s13059-017-1276-1
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author Yamasaki, Amanda E.
Panopoulos, Athanasia D.
Belmonte, Juan Carlos Izpisua
author_facet Yamasaki, Amanda E.
Panopoulos, Athanasia D.
Belmonte, Juan Carlos Izpisua
author_sort Yamasaki, Amanda E.
collection PubMed
description Three recent studies analyzing large-scale collections of human induced pluripotent stem cell lines provide valuable insight into how genetic regulatory variation affects cellular and molecular traits.
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spelling pubmed-55202852017-07-21 Understanding the genetics behind complex human disease with large-scale iPSC collections Yamasaki, Amanda E. Panopoulos, Athanasia D. Belmonte, Juan Carlos Izpisua Genome Biol Research Highlight Three recent studies analyzing large-scale collections of human induced pluripotent stem cell lines provide valuable insight into how genetic regulatory variation affects cellular and molecular traits. BioMed Central 2017-07-20 /pmc/articles/PMC5520285/ /pubmed/28728561 http://dx.doi.org/10.1186/s13059-017-1276-1 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Highlight
Yamasaki, Amanda E.
Panopoulos, Athanasia D.
Belmonte, Juan Carlos Izpisua
Understanding the genetics behind complex human disease with large-scale iPSC collections
title Understanding the genetics behind complex human disease with large-scale iPSC collections
title_full Understanding the genetics behind complex human disease with large-scale iPSC collections
title_fullStr Understanding the genetics behind complex human disease with large-scale iPSC collections
title_full_unstemmed Understanding the genetics behind complex human disease with large-scale iPSC collections
title_short Understanding the genetics behind complex human disease with large-scale iPSC collections
title_sort understanding the genetics behind complex human disease with large-scale ipsc collections
topic Research Highlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520285/
https://www.ncbi.nlm.nih.gov/pubmed/28728561
http://dx.doi.org/10.1186/s13059-017-1276-1
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