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Low oxygen tension increases mitochondrial membrane potential and enhances expression of antioxidant genes and implantation protein of mouse blastocyst cultured in vitro

BACKGROUND: In human IVF, embryos cultured with a lower O(2) tension (5%) can give rise to higher success rates when compared with normoxic conditions (20%). However, the mechanisms behind the beneficial effects of reduced oxygen tension in embryogenesis remain unclear. The aim of this study was to...

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Detalles Bibliográficos
Autores principales: Ma, Yun-Yi, Chen, Huei-Wen, Tzeng, Chii-Ruey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520294/
https://www.ncbi.nlm.nih.gov/pubmed/28728562
http://dx.doi.org/10.1186/s13048-017-0344-1