A gene expression signature distinguishes innate response and resistance to proteasome inhibitors in multiple myeloma

Extensive interindividual variation in response to chemotherapy is a major stumbling block in achieving desirable efficacy in the treatment of cancers, including multiple myeloma (MM). In this study, our goal was to develop a gene expression signature that predicts response specific to proteasome in...

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Detalles Bibliográficos
Autores principales: Mitra, A K, Harding, T, Mukherjee, U K, Jang, J S, Li, Y, HongZheng, R, Jen, J, Sonneveld, P, Kumar, S, Kuehl, W M, Rajkumar, V, Van Ness, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520403/
https://www.ncbi.nlm.nih.gov/pubmed/28665416
http://dx.doi.org/10.1038/bcj.2017.56

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