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Initial sites of hepadnavirus integration into host genome in human hepatocytes and in the woodchuck model of hepatitis B-associated hepatocellular carcinoma

Hepatitis B virus (HBV) and the closely related woodchuck hepatitis virus (WHV) are potent carcinogens that trigger development of primary hepatocellular carcinoma (HCC). The initial sites of hepadnavirus–host genome integration, their diversity and kinetics of formation can be central to virus pers...

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Detalles Bibliográficos
Autores principales:	Chauhan, R, Churchill, N D, Mulrooney-Cousins, P M, Michalak, T I
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520499/ https://www.ncbi.nlm.nih.gov/pubmed/28414318 http://dx.doi.org/10.1038/oncsis.2017.22

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