Drosophila caspase activity is required independently of apoptosis to produce active TNF/Eiger during nociceptive sensitization

Tumor necrosis factor (TNF) signaling is required for inflammatory nociceptive (pain) sensitization in Drosophila and vertebrates. Nociceptive sensitization in Drosophila larvae following UV-induced tissue damage is accompanied by epidermal apoptosis and requires epidermal-derived TNF/Eiger and the...

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Detalles Bibliográficos
Autores principales: Jo, Juyeon, Im, Seol Hee, Babcock, Daniel T, Iyer, Srividya C, Gunawan, Felona, Cox, Daniel N, Galko, Michael J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520682/
https://www.ncbi.nlm.nih.gov/pubmed/28492538
http://dx.doi.org/10.1038/cddis.2016.474

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