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Ubiquitylation of MFHAS1 by the ubiquitin ligase praja2 promotes M1 macrophage polarization by activating JNK and p38 pathways
Sepsis is a systemic inflammation caused by infection. The balance between M1–M2 macrophage polarization has an essential role in the pathogenesis of sepsis. However, the exact mechanism underlying macrophage polarization is unclear. We previously showed that levels of malignant fibrous histiocytoma...
Autores principales: | Zhong, Jing, Wang, Huihui, Chen, Wankun, Sun, Zhirong, Chen, Jiawei, Xu, Yajun, Weng, Meilin, Shi, Qiqing, Ma, Duan, Miao, Changhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520684/ https://www.ncbi.nlm.nih.gov/pubmed/28471450 http://dx.doi.org/10.1038/cddis.2017.102 |
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