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MiR-130a-3p attenuates activation and induces apoptosis of hepatic stellate cells in nonalcoholic fibrosing steatohepatitis by directly targeting TGFBR1 and TGFBR2

Nonalcoholic fibrosing steatohepatitis is a uniform process that occurs throughout nonalcoholic fatty liver disease (NAFLD). MicroRNAs (miRNAs) have been shown to be involved in the biological processes, but the role and molecular mechanism of miRNAs in NAFLD are not entirely clear. In this study, w...

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Detalles Bibliográficos
Autores principales: Wang, Yang, Du, Jinghua, Niu, Xuemin, Fu, Na, Wang, Rongqi, Zhang, Yuguo, Zhao, Suxian, Sun, Dianxing, Nan, Yuemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520685/
https://www.ncbi.nlm.nih.gov/pubmed/28518142
http://dx.doi.org/10.1038/cddis.2017.10