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Enhanced neuroprotective efficacy of bone marrow mesenchymal stem cells co-overexpressing BDNF and VEGF in a rat model of cardiac arrest-induced global cerebral ischemia

Cardiac arrest-induced global cerebral ischemia injury (CA-GCII) usually leads to a poor neurological outcome without an effective treatment. Bone marrow-derived mesenchymal stem cells (BMMSCs) may provide a potential cell-based therapy against neurologic disorders through induction of brain-derived...

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Detalles Bibliográficos
Autores principales: Zhou, Lili, Lin, Qingming, Wang, Peng, Yao, Lan, Leong, Kahong, Tan, Zhiqun, Huang, Zitong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520708/
https://www.ncbi.nlm.nih.gov/pubmed/28492549
http://dx.doi.org/10.1038/cddis.2017.184