ASIC1 and ASIC3 contribute to acidity-induced EMT of pancreatic cancer through activating Ca(2+)/RhoA pathway

Extracellular acid can have important effects on cancer cells. Acid-sensing ion channels (ASICs), which emerged as key receptors for extracellular acidic pH, are differently expressed during various diseases and have been implicated in underlying pathogenesis. This study reports that ASIC1 and ASIC3...

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Detalles Bibliográficos
Autores principales: Zhu, Shuai, Zhou, Hai-Yun, Deng, Shi-Chang, Deng, Shi-Jiang, He, Chi, Li, Xiang, Chen, Jing-Yuan, Jin, Yan, Hu, Zhuang-Li, Wang, Fang, Wang, Chun-You, Zhao, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520710/
https://www.ncbi.nlm.nih.gov/pubmed/28518134
http://dx.doi.org/10.1038/cddis.2017.189

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