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Glycolysis regulates the expansion of myeloid-derived suppressor cells in tumor-bearing hosts through prevention of ROS-mediated apoptosis

Immunotherapy aiming to rescue or boost antitumor immunity is an emerging strategy for treatment of cancers. The efficacy of immunotherapy is strongly controlled by the immunological milieu of cancer patients. Myeloid-derived suppressor cells (MDSCs) are heterogeneous immature myeloid cell populatio...

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Detalles Bibliográficos
Autores principales: Jian, Shiou-Ling, Chen, Wei-Wei, Su, Yu-Chia, Su, Yu-Wen, Chuang, Tsung-Hsien, Hsu, Shu-Ching, Huang, Li-Rung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520713/
https://www.ncbi.nlm.nih.gov/pubmed/28492541
http://dx.doi.org/10.1038/cddis.2017.192