Cargando…

Furanodienone induces G0/G1 arrest and causes apoptosis via the ROS/MAPKs-mediated caspase-dependent pathway in human colorectal cancer cells: a study in vitro and in vivo

Furanodienone, a major bioactive constituents of sesquiterpene derived from Rhizoma Curcumae, has been proven to possess the potent anticancer efficacy on human breast cancer cells. Here, we investigated the cytotoxicity of furanodienone on human colorectal carcinoma cell lines in vitro and in vivo,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiang, Ying, Wang, Xiaoqin, Hu, Daode
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520734/ https://www.ncbi.nlm.nih.gov/pubmed/28542135 http://dx.doi.org/10.1038/cddis.2017.220

Ejemplares similares

Peiminine Induces G0/G1-Phase Arrest, Apoptosis, and Autophagy via the ROS/JNK Signaling Pathway in Human Osteosarcoma Cells in Vitro and in Vivo
por: Yu, Lei, et al.
Publicado: (2021)

The novel mechanism of anticancer effect on gastric cancer through inducing G0/G1 cell cycle arrest and caspase-dependent apoptosis in vitro and in vivo by methionine enkephalin
por: Wang, Xiaonan, et al.
Publicado: (2018)

Propranolol induced G0/G1/S phase arrest and apoptosis in melanoma cells via AKT/MAPK pathway
por: Zhou, Chengfang, et al.
Publicado: (2016)

Antipsychotic Drug Trifluoperazine Suppresses Colorectal Cancer by Inducing G0/G1 Arrest and Apoptosis
por: Xia, Yong, et al.
Publicado: (2019)

Picropodophyllotoxin Induces G1 Cell Cycle Arrest and Apoptosis in Human Colorectal Cancer Cells via ROS Generation and Activation of p38 MAPK Signaling Pathway
por: Lee, Seung-On, et al.
Publicado: (2021)

Escin induces caspase-dependent apoptosis and autophagy through the ROS/p38 MAPK signalling pathway in human osteosarcoma cells in vitro and in vivo
por: Zhu, Jian, et al.
Publicado: (2017)

Combination of anlotinib and gemcitabine promotes the G0/G1 cell cycle arrest and apoptosis of intrahepatic cholangiocarcinoma in vitro
por: Fan, Shanshan, et al.
Publicado: (2021)

Luteoloside Induces G0/G1 Phase Arrest of Neuroblastoma Cells by Targeting p38 MAPK
por: He, Ya, et al.
Publicado: (2023)

Induction of ROS mediated genomic instability, apoptosis and G0/G1 cell cycle arrest by erbium oxide nanoparticles in human hepatic Hep-G2 cancer cells
por: Safwat, Gehan, et al.
Publicado: (2022)

Pterostilbene Simultaneously Induced G0/G1-Phase Arrest and MAPK-Mediated Mitochondrial-Derived Apoptosis in Human Acute Myeloid Leukemia Cell Lines
por: Hsiao, Pei-Ching, et al.
Publicado: (2014)

Erianin induces G2/M-phase arrest, apoptosis, and autophagy via the ROS/JNK signaling pathway in human osteosarcoma cells in vitro and in vivo
por: Wang, H, et al.
Publicado: (2016)

A new Prenylated Flavonoid induces G0/G1 arrest and apoptosis through p38/JNK MAPK pathways in Human Hepatocellular Carcinoma cells
por: Wang, Di, et al.
Publicado: (2017)

Static Mechanical Stress Induces Apoptosis in Rat Endplate Chondrocytes through MAPK and Mitochondria-Dependent Caspase Activation Signaling Pathways
por: Kong, Dechao, et al.
Publicado: (2013)

HOI-02 induces apoptosis and G2-M arrest in esophageal cancer mediated by ROS
por: Zhang, C, et al.
Publicado: (2015)

Luteolin Shifts Oxaliplatin-Induced Cell Cycle Arrest at G(0)/G(1) to Apoptosis in HCT116 Human Colorectal Carcinoma Cells
por: Jang, Chan Ho, et al.
Publicado: (2019)

Casticin induces apoptosis and G0/G1 cell cycle arrest in gallbladder cancer cells
por: Song, Xiao-ling, et al.
Publicado: (2017)

Polypeptide Fraction from Arca subcrenata Induces Apoptosis and G2/M Phase Arrest in HeLa Cells via ROS-Mediated MAPKs Pathways
por: Hu, Xianjing, et al.
Publicado: (2015)

The roles of p38MAPK and caspase-3 in DADS-induced apoptosis in human HepG2 cells
por: Ji, Chunxiao, et al.
Publicado: (2010)

[6]-Gingerol induces Caspase-Dependent Apoptosis in Bladder Cancer cells via MAPK and ROS Signaling
por: Choi, Na Ri, et al.
Publicado: (2022)

Orientin Induces G0/G1 Cell Cycle Arrest and Mitochondria Mediated Intrinsic Apoptosis in Human Colorectal Carcinoma HT29 Cells
por: Thangaraj, Kalaiyarasu, et al.
Publicado: (2019)

Advanced Oxidation Protein Products Induce G1/G0-Phase Arrest in Ovarian Granulosa Cells via the ROS-JNK/p38 MAPK-p21 Pathway in Premature Ovarian Insufficiency
por: Zhou, Xing-Yu, et al.
Publicado: (2021)

Patchouli alcohol induces G(0) /G(1) cell cycle arrest and apoptosis in vincristine‐resistant non‐small cell lung cancer through ROS‐mediated DNA damage
por: Liang, Chi‐Yen, et al.
Publicado: (2023)

Moxidectin inhibits glioma cell viability by inducing G0/G1 cell cycle arrest and apoptosis
por: Song, Dandan, et al.
Publicado: (2018)

Discovery of Dihydropyrrol-2-ones as Novel G0/G1-Phase Arresting Agents Inducing Apoptosis
por: Yang, Danni, et al.
Publicado: (2019)

Screening of Apoptosis Pathway-Mediated Anti-Proliferative Activity of the Phytochemical Compound Furanodienone against Human Non-Small Lung Cancer A-549 Cells
por: Al Saqr, Ahmed, et al.
Publicado: (2022)

Stimulation of ROS Generation by Extract of Warburgia ugandensis Leading to G(0)/G(1) Cell Cycle Arrest and Antiproliferation in A549 Cells
por: Zhang, Yong-Li, et al.
Publicado: (2021)

Impact of Mitochondria-Mediated Apoptosis in U251 Cell Cycle Arrest in G1 Stage and Caspase Activation
por: Zhang, Lei, et al.
Publicado: (2015)

δ‐Tocotrienol sensitizes and re‐sensitizes ovarian cancer cells to cisplatin via induction of G1 phase cell cycle arrest and ROS/MAPK‐mediated apoptosis
por: Fontana, Fabrizio, et al.
Publicado: (2021)

Giardia duodenalis-induced G0/G1 intestinal epithelial cell cycle arrest and apoptosis involve activation of endoplasmic reticulum stress in vitro
por: Yu, Shuyuan, et al.
Publicado: (2023)

Robustaflavone induces G0/G1 cell cycle arrest and apoptosis in human umbilical vein endothelial cells and exhibits anti-angiogenic effects in vivo
por: Sim, Woo Kyung, et al.
Publicado: (2020)

G0/G1 arrest and apoptosis induced by SARS-CoV 3b protein in transfected cells
por: Yuan, Xiaoling, et al.
Publicado: (2005)

Oleanolic acid induces mitochondrial-dependent apoptosis and G0/G1 phase arrest in gallbladder cancer cells
por: Li, Huai-Feng, et al.
Publicado: (2015)

Podophyllotoxin Induces ROS-Mediated Apoptosis and Cell Cycle Arrest in Human Colorectal Cancer Cells via p38 MAPK Signaling
por: Lee, Seung-On, et al.
Publicado: (2021)

Isolinderalactone Induces Apoptosis, Autophagy, Cell Cycle Arrest and MAPK Activation through ROS–Mediated Signaling in Colorectal Cancer Cell Lines
por: Chen, Jith-Shyan, et al.
Publicado: (2023)

Inhibition of Growth of Colon Tumors and Proliferation of HT-29 Cells by Warburgia ugandensis Extract through Mediating G(0)/G(1) Cell Cycle Arrest, Cell Apoptosis, and Intracellular ROS Generation
por: Zhang, Yongli, et al.
Publicado: (2021)

Polyphyllin VII induces apoptosis in HepG2 cells through ROS-mediated mitochondrial dysfunction and MAPK pathways
por: Zhang, Chao, et al.
Publicado: (2016)

Jianpi Huayu Decoction Inhibits Proliferation in Human Colorectal Cancer Cells (SW480) by Inducing G0/G1-Phase Cell Cycle Arrest and Apoptosis
por: Xi, Song-yang, et al.
Publicado: (2015)

Chelidonine Induces Caspase-Dependent and Caspase-Independent Cell Death through G(2/M) Arrest in the T98G Human Glioblastoma Cell Line
por: Lee, Yeon-Kyeong, et al.
Publicado: (2019)

Resveratrol inhibits proliferation in human colorectal carcinoma cells by inducing G(1)/S-phase cell cycle arrest and apoptosis through caspase/cyclin-CDK pathways
por: LIU, BIN, et al.
Publicado: (2014)

Metformin Induced AMPK Activation, G0/G1 Phase Cell Cycle Arrest and the Inhibition of Growth of Esophageal Squamous Cell Carcinomas In Vitro and In Vivo
por: Cai, Xianbin, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_ip782ffmknua9s7ab7favllkb7