Extensive translation of circular RNAs driven by N(6)-methyladenosine

Extensive pre-mRNA back-splicing generates numerous circular RNAs (circRNAs) in human transcriptome. However, the biological functions of these circRNAs remain largely unclear. Here we report that N(6)-methyladenosine (m(6)A), the most abundant base modification of RNA, promotes efficient initiation...

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Detalles Bibliográficos
Autores principales: Yang, Yun, Fan, Xiaojuan, Mao, Miaowei, Song, Xiaowei, Wu, Ping, Zhang, Yang, Jin, Yongfeng, Yang, Yi, Chen, Ling-Ling, Wang, Yang, Wong, Catherine CL, Xiao, Xinshu, Wang, Zefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520850/
https://www.ncbi.nlm.nih.gov/pubmed/28281539
http://dx.doi.org/10.1038/cr.2017.31

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