Baf60b-mediated ATM-p53 activation blocks cell identity conversion by sensing chromatin opening

Lineage conversion by expression of lineage-specific transcription factors is a process of epigenetic remodeling that has low efficiency. The mechanism by which a cell resists lineage conversion is largely unknown. Using hepatic-specific transcription factors Foxa3, Hnf1α and Gata4 (3TF) to induce h...

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Detalles Bibliográficos
Autores principales: Ji, Shuyi, Zhu, Linying, Gao, Yimeng, Zhang, Xiaoran, Yan, Yupeng, Cen, Jin, Li, Rongxia, Zeng, Rong, Liao, Lujian, Hou, Chunhui, Gao, Yawei, Gao, Shaorong, Wei, Gang, Hui, Lijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520852/
https://www.ncbi.nlm.nih.gov/pubmed/28303890
http://dx.doi.org/10.1038/cr.2017.36

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