MicroRNA-29a induces loss of 5-hydroxymethylcytosine and promotes metastasis of hepatocellular carcinoma through a TET–SOCS1–MMP9 signaling axis

Ten eleven translocation (TET) enzymes convert 5-methylcytosine (5-mC) to 5-hydroxy-methylcytosine (5-hmC) and have crucial roles in biological and pathological processes by mediating DNA demethylation, however, the functional role of this epigenetic mark and the related enzymes in hepatocellular ca...

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Detalles Bibliográficos
Autores principales: Chen, Qing, Yin, Dan, Zhang, Yong, Yu, Lei, Li, Xue-Dong, Zhou, Zheng-Jun, Zhou, Shao-Lai, Gao, Dong-Mei, Hu, Jie, Jin, Cheng, Wang, Zheng, Shi, Ying-Hong, Cao, Ya, Fan, Jia, Dai, Zhi, Zhou, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520877/
https://www.ncbi.nlm.nih.gov/pubmed/28661477
http://dx.doi.org/10.1038/cddis.2017.142

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