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Essential but partially redundant roles for POU4F1/Brn-3a and POU4F2/Brn-3b transcription factors in the developing heart
Congenital heart defects contribute to embryonic or neonatal lethality but due to the complexity of cardiac development, the molecular changes associated with such defects are not fully understood. Here, we report that transcription factors (TFs) Brn-3a (POU4F1) and Brn-3b (POU4F2) are important for...
Autores principales: | Maskell, Lauren J, Qamar, Kashif, Babakr, Aram A, Hawkins, Thomas A, Heads, Richard J, Budhram-Mahadeo, Vishwanie S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520879/ https://www.ncbi.nlm.nih.gov/pubmed/28594399 http://dx.doi.org/10.1038/cddis.2017.185 |
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