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Oocyte-specific deletion of furin leads to female infertility by causing early secondary follicle arrest in mice

The process of follicular development involves communications between oocyte and surrounding granulosa cells. FURIN is a member of the family of proprotein convertases that is involved in the activation of a large number of zymogens and proproteins by cleavage at its recognition motif. To investigat...

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Detalles Bibliográficos
Autores principales: Meng, Tie-Gang, Hu, Meng-Wen, Ma, Xue-Shan, Huang, Lin, Liang, Qiu-Xia, Yuan, Yue, Hou, Yi, Wang, Hongmei, Schatten, Heide, Wang, Zhen-Bo, Sun, Qing-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520891/
https://www.ncbi.nlm.nih.gov/pubmed/28569793
http://dx.doi.org/10.1038/cddis.2017.231