Loss of epidermal AP1 transcription factor function reduces filaggrin level, alters chemokine expression and produces an ichthyosis-related phenotype

AP1 transcription factors are important controllers of epidermal differentiation. Multiple family members are expressed in the epidermis in a differentiation-dependent manner, where they function to regulate gene expression. To study the role of AP1 factor signaling, TAM67 (dominant-negative c-jun)...

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Detalles Bibliográficos
Autores principales: Young, Christina A, Rorke, Ellen A, Adhikary, Gautam, Xu, Wen, Eckert, Richard L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520897/
https://www.ncbi.nlm.nih.gov/pubmed/28569792
http://dx.doi.org/10.1038/cddis.2017.238

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