ARRDC4 regulates enterovirus 71-induced innate immune response by promoting K63 polyubiquitination of MDA5 through TRIM65

Enterovirus 71 (EV71) is the main causative agent of hand, foot and mouth disease (HFMD), which induces significantly elevated levels of cytokines and chemokines, leading to local or system inflammation and severe complications, whereas the underlying regulatory mechanisms and the inflammatory patho...

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Detalles Bibliográficos
Autores principales: Meng, Jun, Yao, Zhenyu, He, Yaqing, Zhang, Renli, Zhang, Yanwei, Yao, Xiangjie, Yang, Hong, Chen, Long, Zhang, Zhen, Zhang, Hailong, Bao, Xueqin, Hu, Gang, Wu, Tangchun, Cheng, Jinquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520913/
https://www.ncbi.nlm.nih.gov/pubmed/28594402
http://dx.doi.org/10.1038/cddis.2017.257

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