Chronic glucocorticoid exposure activates BK-NLRP1 signal involving in hippocampal neuron damage

BACKGROUND: Neuroinflammation mediated by NLRP1 (nucleotide-binding oligomerization domain (NOD)-like receptor protein 1) inflammasome plays an important role in many neurological diseases such as Parkinson’s disease (PD) and Alzheimer’s disease (AD). Our previous studies showed that chronic glucoco...

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Detalles Bibliográficos
Autores principales: Zhang, Biqiong, Zhang, Yaodong, Wu, Wenning, Xu, Tanzhen, Yin, Yanyan, Zhang, Junyan, Huang, Dake, Li, Weizu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521122/
https://www.ncbi.nlm.nih.gov/pubmed/28732502
http://dx.doi.org/10.1186/s12974-017-0911-9

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