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Adenocarcinoma of Lung Presenting as Lambert-Eaton Myasthenic Syndrome
Lambert-Eaton myasthenic syndrome (LEMS) is a paraneoplastic neuromuscular junction disorder. LEMS presents with muscular weakness and fatigability, mainly involving the proximal lower limbs. There are 2 types of LEMS depending on the etiology: paraneoplastic and idiopathic. The paraneoplastic form,...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521354/ https://www.ncbi.nlm.nih.gov/pubmed/28785598 http://dx.doi.org/10.1177/2324709617721251 |
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author | Bukhari, Sumera Soomro, Rabia Fawwad, Shaikh Alvarez, Chikezie Wallach, Sara |
author_facet | Bukhari, Sumera Soomro, Rabia Fawwad, Shaikh Alvarez, Chikezie Wallach, Sara |
author_sort | Bukhari, Sumera |
collection | PubMed |
description | Lambert-Eaton myasthenic syndrome (LEMS) is a paraneoplastic neuromuscular junction disorder. LEMS presents with muscular weakness and fatigability, mainly involving the proximal lower limbs. There are 2 types of LEMS depending on the etiology: paraneoplastic and idiopathic. The paraneoplastic form, which constitutes more than a half of the cases, is mostly associated with intrathoracic neoplasms. Most cases are seen in patients with small cell lung cancer; other subtypes of lung cancer are extremely rare. In this article, we report a case of LEMS as a rare association with adenocarcinoma of the lung. |
format | Online Article Text |
id | pubmed-5521354 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-55213542017-08-07 Adenocarcinoma of Lung Presenting as Lambert-Eaton Myasthenic Syndrome Bukhari, Sumera Soomro, Rabia Fawwad, Shaikh Alvarez, Chikezie Wallach, Sara J Investig Med High Impact Case Rep Case Report Lambert-Eaton myasthenic syndrome (LEMS) is a paraneoplastic neuromuscular junction disorder. LEMS presents with muscular weakness and fatigability, mainly involving the proximal lower limbs. There are 2 types of LEMS depending on the etiology: paraneoplastic and idiopathic. The paraneoplastic form, which constitutes more than a half of the cases, is mostly associated with intrathoracic neoplasms. Most cases are seen in patients with small cell lung cancer; other subtypes of lung cancer are extremely rare. In this article, we report a case of LEMS as a rare association with adenocarcinoma of the lung. SAGE Publications 2017-07-14 /pmc/articles/PMC5521354/ /pubmed/28785598 http://dx.doi.org/10.1177/2324709617721251 Text en © 2017 American Federation for Medical Research http://creativecommons.org/licenses/by/4.0/ This article is distributed under the terms of the Creative Commons Attribution 4.0 License (http://www.creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Case Report Bukhari, Sumera Soomro, Rabia Fawwad, Shaikh Alvarez, Chikezie Wallach, Sara Adenocarcinoma of Lung Presenting as Lambert-Eaton Myasthenic Syndrome |
title | Adenocarcinoma of Lung Presenting as Lambert-Eaton Myasthenic Syndrome |
title_full | Adenocarcinoma of Lung Presenting as Lambert-Eaton Myasthenic Syndrome |
title_fullStr | Adenocarcinoma of Lung Presenting as Lambert-Eaton Myasthenic Syndrome |
title_full_unstemmed | Adenocarcinoma of Lung Presenting as Lambert-Eaton Myasthenic Syndrome |
title_short | Adenocarcinoma of Lung Presenting as Lambert-Eaton Myasthenic Syndrome |
title_sort | adenocarcinoma of lung presenting as lambert-eaton myasthenic syndrome |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521354/ https://www.ncbi.nlm.nih.gov/pubmed/28785598 http://dx.doi.org/10.1177/2324709617721251 |
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