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Attitudes among transplant professionals regarding shifting paradigms in eligibility criteria for live kidney donation

BACKGROUND: The transplant community increasingly accepts extended criteria live kidney donors, however, great (geographical) differences are present in policies regarding the acceptance of these donors, and guidelines do not offer clarity. The aim of this survey was to reveal these differences and...

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Autores principales: Lafranca, Jeffrey A., Spoon, Emerentia Q. W., van de Wetering, Jacqueline, IJzermans, Jan N. M., Dor, Frank J. M. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521829/
https://www.ncbi.nlm.nih.gov/pubmed/28732093
http://dx.doi.org/10.1371/journal.pone.0181846
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author Lafranca, Jeffrey A.
Spoon, Emerentia Q. W.
van de Wetering, Jacqueline
IJzermans, Jan N. M.
Dor, Frank J. M. F.
author_facet Lafranca, Jeffrey A.
Spoon, Emerentia Q. W.
van de Wetering, Jacqueline
IJzermans, Jan N. M.
Dor, Frank J. M. F.
author_sort Lafranca, Jeffrey A.
collection PubMed
description BACKGROUND: The transplant community increasingly accepts extended criteria live kidney donors, however, great (geographical) differences are present in policies regarding the acceptance of these donors, and guidelines do not offer clarity. The aim of this survey was to reveal these differences and to get an insight in both centre policies as well as personal beliefs of transplant professionals. METHODS: An online survey was sent to 1128 ESOT-members. Questions were included about several extended donor criteria; overweight/obesity, older age, vascular multiplicity, minors as donors and comorbidities; hypertension, impaired fasting glucose, kidney stones, malignancies and renal cysts. Comparisons were made between transplant centres of three regions in Europe and between Europe and other countries worldwide. RESULTS: 331 questionnaires were completed by professionals from 55 countries. Significant differences exist between regions in Europe in acceptance of donors with several extended criteria. Median refusal rate for potential live donors is 15%. Furthermore, differences are seen regarding pre-operative work-up, both in specialists who perform screening as in preoperative imaging. CONCLUSIONS: Remarkably, 23.4% of transplant professionals sometimes deviate from their centre policy, resulting in more or less comparable personal beliefs regarding extended criteria. Variety is seen, proving the need for a standardized approach in selection, preferably evidence based.
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spelling pubmed-55218292017-08-07 Attitudes among transplant professionals regarding shifting paradigms in eligibility criteria for live kidney donation Lafranca, Jeffrey A. Spoon, Emerentia Q. W. van de Wetering, Jacqueline IJzermans, Jan N. M. Dor, Frank J. M. F. PLoS One Research Article BACKGROUND: The transplant community increasingly accepts extended criteria live kidney donors, however, great (geographical) differences are present in policies regarding the acceptance of these donors, and guidelines do not offer clarity. The aim of this survey was to reveal these differences and to get an insight in both centre policies as well as personal beliefs of transplant professionals. METHODS: An online survey was sent to 1128 ESOT-members. Questions were included about several extended donor criteria; overweight/obesity, older age, vascular multiplicity, minors as donors and comorbidities; hypertension, impaired fasting glucose, kidney stones, malignancies and renal cysts. Comparisons were made between transplant centres of three regions in Europe and between Europe and other countries worldwide. RESULTS: 331 questionnaires were completed by professionals from 55 countries. Significant differences exist between regions in Europe in acceptance of donors with several extended criteria. Median refusal rate for potential live donors is 15%. Furthermore, differences are seen regarding pre-operative work-up, both in specialists who perform screening as in preoperative imaging. CONCLUSIONS: Remarkably, 23.4% of transplant professionals sometimes deviate from their centre policy, resulting in more or less comparable personal beliefs regarding extended criteria. Variety is seen, proving the need for a standardized approach in selection, preferably evidence based. Public Library of Science 2017-07-21 /pmc/articles/PMC5521829/ /pubmed/28732093 http://dx.doi.org/10.1371/journal.pone.0181846 Text en © 2017 Lafranca et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Lafranca, Jeffrey A.
Spoon, Emerentia Q. W.
van de Wetering, Jacqueline
IJzermans, Jan N. M.
Dor, Frank J. M. F.
Attitudes among transplant professionals regarding shifting paradigms in eligibility criteria for live kidney donation
title Attitudes among transplant professionals regarding shifting paradigms in eligibility criteria for live kidney donation
title_full Attitudes among transplant professionals regarding shifting paradigms in eligibility criteria for live kidney donation
title_fullStr Attitudes among transplant professionals regarding shifting paradigms in eligibility criteria for live kidney donation
title_full_unstemmed Attitudes among transplant professionals regarding shifting paradigms in eligibility criteria for live kidney donation
title_short Attitudes among transplant professionals regarding shifting paradigms in eligibility criteria for live kidney donation
title_sort attitudes among transplant professionals regarding shifting paradigms in eligibility criteria for live kidney donation
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521829/
https://www.ncbi.nlm.nih.gov/pubmed/28732093
http://dx.doi.org/10.1371/journal.pone.0181846
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