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Dysregulation of pulmonary endothelial protein C receptor and thrombomodulin in severe falciparum malaria-associated ARDS relevant to hemozoin

To investigate the role of the protein C system, endothelial protein C receptor (EPCR) and thrombomodulin (TM) in the pathogenesis of malaria-associated acute respiratory distress syndrome (ARDS) in relation to hemozoin and proinflammatory cytokines-induced type II pneumocyte injury and -aggravated...

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Detalles Bibliográficos
Autores principales: Maknitikul, Sitang, Luplertlop, Natthanej, Grau, Georges E. R., Ampawong, Sumate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521846/
https://www.ncbi.nlm.nih.gov/pubmed/28732053
http://dx.doi.org/10.1371/journal.pone.0181674