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Inherent limitations of probabilistic models for protein-DNA binding specificity
The specificities of transcription factors are most commonly represented with probabilistic models. These models provide a probability for each base occurring at each position within the binding site and the positions are assumed to contribute independently. The model is simple and intuitive and is...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521849/ https://www.ncbi.nlm.nih.gov/pubmed/28686588 http://dx.doi.org/10.1371/journal.pcbi.1005638 |