Processing closely spaced lesions during Nucleotide Excision Repair triggers mutagenesis in E. coli

It is generally assumed that most point mutations are fixed when damage containing template DNA undergoes replication, either right at the fork or behind the fork during gap filling. Here we provide genetic evidence for a pathway, dependent on Nucleotide Excision Repair, that induces mutations when...

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Detalles Bibliográficos
Autores principales: Janel-Bintz, Régine, Napolitano, Rita L., Isogawa, Asako, Fujii, Shingo, Fuchs, Robert P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521853/
https://www.ncbi.nlm.nih.gov/pubmed/28686598
http://dx.doi.org/10.1371/journal.pgen.1006881

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