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Mechanisms of Insulin Resistance in Primary and Secondary Nonalcoholic Fatty Liver

Nonalcoholic fatty liver disease is associated with hepatic insulin resistance and may result primarily from increased hepatic de novo lipogenesis (PRIM) or secondarily from adipose tissue lipolysis (SEC). We studied mice with hepatocyte- or adipocyte-specific SREBP-1c overexpression as models of PR...

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Detalles Bibliográficos
Autores principales:	Jelenik, Tomas, Kaul, Kirti, Séquaris, Gilles, Flögel, Ulrich, Phielix, Esther, Kotzka, Jörg, Knebel, Birgit, Fahlbusch, Pia, Hörbelt, Tina, Lehr, Stefan, Reinbeck, Anna Lena, Müller-Wieland, Dirk, Esposito, Irene, Shulman, Gerald I., Szendroedi, Julia, Roden, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2017
Materias:	Pathophysiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521856/ https://www.ncbi.nlm.nih.gov/pubmed/28490610 http://dx.doi.org/10.2337/db16-1147

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