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Case report: multiple systemic disseminated tuberculosis mimicking lymphoma on 18F-FDG PET/CT

RATIONALE: (18)F-fluorodeoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT) has an important role in the diagnosis of various malignancies. However, F-18 FDG can also exhibit intense accumulation in tissues in inflammatory conditions such as active tuberculosis (TB) and sa...

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Detalles Bibliográficos
Autores principales: Hou, Shasha, Shen, Jie, Tan, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521880/
https://www.ncbi.nlm.nih.gov/pubmed/28723740
http://dx.doi.org/10.1097/MD.0000000000007248
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author Hou, Shasha
Shen, Jie
Tan, Jian
author_facet Hou, Shasha
Shen, Jie
Tan, Jian
author_sort Hou, Shasha
collection PubMed
description RATIONALE: (18)F-fluorodeoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT) has an important role in the diagnosis of various malignancies. However, F-18 FDG can also exhibit intense accumulation in tissues in inflammatory conditions such as active tuberculosis (TB) and sarcoidosis. PATIENT CONCERNS: We report a case of a 52-year-old female with irritable cough. CT showed a lung mass with multiple bilateral lung nodules, and sarcoidosis was suspected. F-18 FDG PET/CT was undertaken for the diagnosis and showed intense uptake of FDG in the mass in the lower lobe of the right lung, multiple lymph nodes, liver, and spleen. The maximum standardized uptake value of F-18 FDG was 43.58. This pattern of involvement most likely represents lymphomatous involvement. DIAGNOSES: Histopathology suggested tubercular involvement. INTERVENTION AND OUTCOMES: The patient received anti-TB treatment and recovered. LESSONS: Abovementioned extent and distribution of F-18 FDG in tubercular lesion is relatively rare, thus, one must be observant and aware with regards to TB being a strong mimic of lymphoma in endemic regions.
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spelling pubmed-55218802017-07-31 Case report: multiple systemic disseminated tuberculosis mimicking lymphoma on 18F-FDG PET/CT Hou, Shasha Shen, Jie Tan, Jian Medicine (Baltimore) 6800 RATIONALE: (18)F-fluorodeoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT) has an important role in the diagnosis of various malignancies. However, F-18 FDG can also exhibit intense accumulation in tissues in inflammatory conditions such as active tuberculosis (TB) and sarcoidosis. PATIENT CONCERNS: We report a case of a 52-year-old female with irritable cough. CT showed a lung mass with multiple bilateral lung nodules, and sarcoidosis was suspected. F-18 FDG PET/CT was undertaken for the diagnosis and showed intense uptake of FDG in the mass in the lower lobe of the right lung, multiple lymph nodes, liver, and spleen. The maximum standardized uptake value of F-18 FDG was 43.58. This pattern of involvement most likely represents lymphomatous involvement. DIAGNOSES: Histopathology suggested tubercular involvement. INTERVENTION AND OUTCOMES: The patient received anti-TB treatment and recovered. LESSONS: Abovementioned extent and distribution of F-18 FDG in tubercular lesion is relatively rare, thus, one must be observant and aware with regards to TB being a strong mimic of lymphoma in endemic regions. Wolters Kluwer Health 2017-07-21 /pmc/articles/PMC5521880/ /pubmed/28723740 http://dx.doi.org/10.1097/MD.0000000000007248 Text en Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle 6800
Hou, Shasha
Shen, Jie
Tan, Jian
Case report: multiple systemic disseminated tuberculosis mimicking lymphoma on 18F-FDG PET/CT
title Case report: multiple systemic disseminated tuberculosis mimicking lymphoma on 18F-FDG PET/CT
title_full Case report: multiple systemic disseminated tuberculosis mimicking lymphoma on 18F-FDG PET/CT
title_fullStr Case report: multiple systemic disseminated tuberculosis mimicking lymphoma on 18F-FDG PET/CT
title_full_unstemmed Case report: multiple systemic disseminated tuberculosis mimicking lymphoma on 18F-FDG PET/CT
title_short Case report: multiple systemic disseminated tuberculosis mimicking lymphoma on 18F-FDG PET/CT
title_sort case report: multiple systemic disseminated tuberculosis mimicking lymphoma on 18f-fdg pet/ct
topic 6800
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521880/
https://www.ncbi.nlm.nih.gov/pubmed/28723740
http://dx.doi.org/10.1097/MD.0000000000007248
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