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Selective inhibition of matrix metalloproteinase-2 in the multiple myeloma-bone microenvironment

Multiple myeloma is a plasma cell malignancy that homes aberrantly to bone causing extensive skeletal destruction. Despite the development of novel therapeutic agents that have significantly improved overall survival, multiple myeloma remains an incurable disease. Matrix metalloproteinase-2 (MMP-2)...

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Detalles Bibliográficos
Autores principales: Shay, Gemma, Tauro, Marilena, Loiodice, Fulvio, Tortorella, Paolo, Sullivan, Daniel M., Hazlehurst, Lori A., Lynch, Conor C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522031/
https://www.ncbi.nlm.nih.gov/pubmed/28611279
http://dx.doi.org/10.18632/oncotarget.18103