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Selective inhibition of matrix metalloproteinase-2 in the multiple myeloma-bone microenvironment
Multiple myeloma is a plasma cell malignancy that homes aberrantly to bone causing extensive skeletal destruction. Despite the development of novel therapeutic agents that have significantly improved overall survival, multiple myeloma remains an incurable disease. Matrix metalloproteinase-2 (MMP-2)...
Autores principales: | Shay, Gemma, Tauro, Marilena, Loiodice, Fulvio, Tortorella, Paolo, Sullivan, Daniel M., Hazlehurst, Lori A., Lynch, Conor C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522031/ https://www.ncbi.nlm.nih.gov/pubmed/28611279 http://dx.doi.org/10.18632/oncotarget.18103 |
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