Tristetraprolin inhibits mitochondrial function through suppression of α-Synuclein expression in cancer cells

Mitochondrial dynamics play critical roles in maintaining mitochondrial functions. Here, we report a novel mechanism for regulation of mitochondrial dynamics mediated by tristetraprolin (TTP), an AU-rich element (ARE)-binding protein. Overexpression of TTP resulted in elongated mitochondria, down-re...

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Detalles Bibliográficos
Autores principales: Vo, Mai-Tram, Choi, Seong Hee, Lee, Ji-Heon, Hong, Chung Hwan, Kim, Jong Soo, Lee, Unn Hwa, Chung, Hyung-Min, Lee, Byung Ju, Park, Jeong Woo, Cho, Wha Ja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522037/
https://www.ncbi.nlm.nih.gov/pubmed/28410208
http://dx.doi.org/10.18632/oncotarget.16706

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