Upregulated WEE1 protects endothelial cells of colorectal cancer liver metastases

Surgical resection of colorectal cancer liver metastases (CLM) can be curative, yet 80% of patients are unsuitable for this treatment. As angiogenesis is a determinant of CLM progression we isolated endothelial cells from CLM and sought a mechanism which is upregulated, essential for angiogenic prop...

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Detalles Bibliográficos
Autores principales: Webster, Peter J., Littlejohns, Anna T., Gaunt, Hannah J., Young, Richard S., Rode, Baptiste, Ritchie, Judith E., Stead, Lucy F., Harrison, Sally, Droop, Alastair, Martin, Heather L., Tomlinson, Darren C., Hyman, Adam J., Appleby, Hollie L., Boxall, Sally, Bruns, Alexander F., Li, Jing, Prasad, Raj K., Lodge, J. Peter A., Burke, Dermot A., Beech, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522067/
https://www.ncbi.nlm.nih.gov/pubmed/28178688
http://dx.doi.org/10.18632/oncotarget.15039

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