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IK channel activation increases tumor growth and induces differential behavioral responses in two breast epithelial cell lines

Many potassium channel families are over-expressed in cancer, but their mechanistic role in disease progression is poorly understood. Potassium channels modulate membrane potential (V(mem)) and thereby influence calcium ion dynamics and other voltage-sensitive signaling mechanisms, potentially actin...

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Detalles Bibliográficos
Autores principales: Thurber, Amy E., Nelson, Michaela, Frost, Crystal L., Levin, Michael, Brackenbury, William J., Kaplan, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522074/
https://www.ncbi.nlm.nih.gov/pubmed/28415575
http://dx.doi.org/10.18632/oncotarget.16389