Cargando…

Analysis of STAT3 post-translational modifications (PTMs) in human prostate cancer with different Gleason Score

Prostate Cancer (PCa) is a complex and heterogeneous disease. The androgen receptor (AR) and the signal transducer and activator of transcription 3 (STAT3) could be effective targets for PCa therapy. STAT3, a cytoplasmatic latent transcription factor, is a hub protein for several oncogenic signallin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cocchiola, Rossana, Romaniello, Donatella, Grillo, Caterina, Altieri, Fabio, Liberti, Marcello, Magliocca, Fabio Massimo, Chichiarelli, Silvia, Marrocco, Ilaria, Borgoni, Giuseppe, Perugia, Giacomo, Eufemi, Margherita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522088/ https://www.ncbi.nlm.nih.gov/pubmed/28489571 http://dx.doi.org/10.18632/oncotarget.17245

Ejemplares similares

Upregulation of TPX2 by STAT3: Identification of a Novel STAT3 Binding Site
por: Cocchiola, Rossana, et al.
Publicado: (2014)

STAT3 Post-Translational Modifications Drive Cellular Signaling Pathways in Prostate Cancer Cells
por: Cocchiola, Rossana, et al.
Publicado: (2019)

Comparative Analysis of the Interaction between Different Flavonoids and PDIA3
por: Giamogante, Flavia, et al.
Publicado: (2016)

Shmt2: A Stat3 Signaling New Player in Prostate Cancer Energy Metabolism
por: Marrocco, Ilaria, et al.
Publicado: (2019)

β-Hexachlorocyclohexane Drives Carcinogenesis in the Human Normal Bronchial Epithelium Cell Line BEAS-2B
por: Rubini, Elisabetta, et al.
Publicado: (2021)

STAT3, a Hub Protein of Cellular Signaling Pathways, Is Triggered by β-Hexaclorocyclohexane
por: Rubini, Elisabetta, et al.
Publicado: (2018)

Analysis of the interaction of calcitriol with the disulfide isomerase ERp57
por: Gaucci, Elisa, et al.
Publicado: (2016)

Neoadjuvant Chemotherapy in Neuroendocrine Bladder Cancer: A Case Report
por: Prelaj, Arsela, et al.
Publicado: (2016)

ERp57/PDIA3: new insight
por: Chichiarelli, Silvia, et al.
Publicado: (2022)

Ascorbate as a Bioactive Compound in Cancer Therapy: The Old Classic Strikes Back
por: González-Montero, Jaime, et al.
Publicado: (2022)

Tomato and Olive Bioactive Compounds: A Natural Shield against the Cellular Effects Induced by β-Hexachlorocyclohexane-Activated Signaling Pathways
por: Rubini, Elisabetta, et al.
Publicado: (2021)

Protein Disulfide Isomerase A3 (PDIA3): A Pharmacological Target in Glioblastoma?
por: Paglia, Giuliano, et al.
Publicado: (2023)

Ribosome-Directed Therapies in Cancer
por: Temaj, Gazmend, et al.
Publicado: (2022)

Measurement and Clinical Significance of Biomarkers of Oxidative Stress in Humans
por: Marrocco, Ilaria, et al.
Publicado: (2017)

PhosphoSitePlus, 2014: mutations, PTMs and recalibrations
por: Hornbeck, Peter V., et al.
Publicado: (2014)

Proteomic Analysis of Histone Variants and Their PTMs: Strategies and Pitfalls
por: El Kennani, Sara, et al.
Publicado: (2018)

Investigating Crosstalk Among PTMs Provides Novel Insight Into the Structural Basis Underlying the Differential Effects of Nt17 PTMs on Mutant Httex1 Aggregation
por: Chiki, Anass, et al.
Publicado: (2021)

PPARγ in Atherosclerotic Endothelial Dysfunction: Regulatory Compounds and PTMs
por: Luan, Jinwen, et al.
Publicado: (2023)

Potentiation of Low-Dose Doxorubicin Cytotoxicity by Affecting P-Glycoprotein through Caryophyllane Sesquiterpenes in HepG2 Cells: An In Vitro and In Silico Study
por: Di Sotto, Antonella, et al.
Publicado: (2020)

Two distinct modes for propagation of histone PTMs across the cell cycle
por: Alabert, Constance, et al.
Publicado: (2015)

Thiol-based Oxidative Posttranslational Modifications (OxiPTMs) of Plant Proteins
por: Corpas, Francisco J, et al.
Publicado: (2022)

Antioxidant Systems are Regulated by Nitric Oxide-Mediated Post-translational Modifications (NO-PTMs)
por: Begara-Morales, Juan C., et al.
Publicado: (2016)

Editorial: Targeting Protein Post-Translational Modifications (PTMs) for Diagnosis and Treatment of Sepsis
por: Chang, Panpan, et al.
Publicado: (2022)

Role of Host-Mediated Post-Translational Modifications (PTMs) in RNA Virus Pathogenesis
por: Kumar, Ramesh, et al.
Publicado: (2020)

Influence of Ellagitannins Extracted by Pomegranate Fruit on Disulfide Isomerase PDIA3 Activity
por: Altieri, Fabio, et al.
Publicado: (2019)

PTMs in Conversation: Activity and Function of Deubiquitinating Enzymes Regulated via Post-Translational Modifications
por: Kessler, Benedikt M., et al.
Publicado: (2011)

Sorafenib Chemosensitization by Caryophyllane Sesquiterpenes in Liver, Biliary, and Pancreatic Cancer Cells: The Role of STAT3/ABC Transporter Axis
por: Di Giacomo, Silvia, et al.
Publicado: (2022)

β-Caryophyllene Counteracts Chemoresistance Induced by Cigarette Smoke in Triple-Negative Breast Cancer MDA-MB-468 Cells
por: Di Sotto, Antonella, et al.
Publicado: (2022)

β-Hexachlorocyclohexane: A Small Molecule with a Big Impact on Human Cellular Biochemistry
por: Rubini, Elisabetta, et al.
Publicado: (2020)

Identification of ubiquitin/ubiquitin-like protein modification from tandem mass spectra with various PTMs
por: Kang, Chiyong, et al.
Publicado: (2011)

HiLight-PTM: an online application to aid matching peptide pairs with isotopically labelled PTMs
por: Whitwell, Harry J, et al.
Publicado: (2019)

Modulation of STAT3 Signaling, Cell Redox Defenses and Cell Cycle Checkpoints by β-Caryophyllene in Cholangiocarcinoma Cells: Possible Mechanisms Accounting for Doxorubicin Chemosensitization and Chemoprevention
por: Di Sotto, Antonella, et al.
Publicado: (2020)

Ubiquitin-Like Post-Translational Modifications (Ubl-PTMs): Small Peptides with Huge Impact in Liver Fibrosis
por: Lachiondo-Ortega, Sofia, et al.
Publicado: (2019)

Common Post-translational Modifications (PTMs) of Proteins: Analysis by Up-to-Date Analytical Techniques with an Emphasis on Barley
por: Bobalova, Janette, et al.
Publicado: (2023)

Unbiased Phosphoproteome Mining Reveals New Functional Sites of Metabolite-Derived PTMs Involved in MASLD Development
por: Moltó, Eduardo, et al.
Publicado: (2023)

ERp57/GRP58: A protein with multiple functions
por: Turano, Carlo, et al.
Publicado: (2011)

Lectures on Gleason parts
por: Bear, Herbert S
Publicado: (1970)

Dr. S. O. Gleason
Publicado: (1899)

Cribriform pattern does not have a significant impact in Gleason Score ≥7/ISUP Grade ≥2 prostate cancers submitted to radical prostatectomy
por: Flammia, Simone, et al.
Publicado: (2020)

Prognostic Utility of the Gleason Grading System Revisions and Histopathological Factors Beyond Gleason Grade
por: Zelic, Renata, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_3n8e0g8tld7ac5lr3li7l5dof1