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NGS based identification of mutational hotspots for targeted therapy in anaplastic thyroid carcinoma

CONTEXT: Anaplastic thyroid carcinoma (ATC) represents one of the most aggressive carcinomas with no consistent survival benefit when treated with conventional radiochemotherapy. Approaches targeting “oncogene addiction” of ATC are increasingly explored and first promising results have been reported...

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Detalles Bibliográficos
Autores principales: Tiedje, Vera, Ting, Saskia, Herold, Thomas, Synoracki, Sarah, Latteyer, Soeren, Moeller, Lars C., Zwanziger, Denise, Stuschke, Martin, Fuehrer, Dagmar, Schmid, Kurt Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522092/
https://www.ncbi.nlm.nih.gov/pubmed/28489587
http://dx.doi.org/10.18632/oncotarget.17300