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Combating acquired resistance to trastuzumab by an anti-ErbB2 fully human antibody

Trastuzumab resistance is a common problem that impedes the effectiveness of trastuzumab in ErbB2-amplified cancers. About 70% of ErbB2-amplified breast cancers do not respond to trastuzumab (de novo resistance), and the majority of the trastuzumab-responsive cancers progress within 1 year (acquired...

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Detalles Bibliográficos
Autores principales:	Wang, Chao, Wang, Lingfei, Yu, Xiaojie, Zhang, Yajun, Meng, Yanchun, Wang, Huajing, Yang, Yang, Gao, Jie, Wei, Huafeng, Zhao, Jian, Lu, Cuihua, Chen, Han, Sun, Yanping, Li, Bohua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522102/ https://www.ncbi.nlm.nih.gov/pubmed/28514745 http://dx.doi.org/10.18632/oncotarget.17451

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