Self-assembling nanoparticles encapsulating zoledronic acid inhibit mesenchymal stromal cells differentiation, migration and secretion of proangiogenic factors and their interactions with prostate cancer cells

Zoledronic Acid (ZA) rapidly concentrates into the bone and reduces skeletal-related events and pain in bone metastatic prostate cancer (PCa), but exerts only a limited or absent impact as anti-cancer activity. Recently, we developed self-assembling nanoparticles (NPS) encapsulating zoledronic acid...

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Detalles Bibliográficos
Autores principales: Borghese, Cinzia, Casagrande, Naike, Pivetta, Eliana, Colombatti, Alfonso, Boccellino, Mariarosaria, Amler, Evzen, Normanno, Nicola, Caraglia, Michele, De Rosa, Giuseppe, Aldinucci, Donatella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522116/
https://www.ncbi.nlm.nih.gov/pubmed/28477013
http://dx.doi.org/10.18632/oncotarget.17216

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